What layer of the epidermis contains keratohyalin granules?

The layer of the epidermis that contains keratohyalin granules is the Stratum Granulosum. This layer is notable for its distinct appearance and function in the skin's barrier formation. Within the Stratum Granulosum, keratinocytes are undergoing a process called keratinization, where they begin to lose their nuclei and organelles as they produce and accumulate keratohyalin granules. These granules play a critical role in the conversion of keratinocytes into a tougher, protective layer and contribute to the skin's barrier against water loss and external pathogens.

Keratohyalin granules contain proteins that promote the aggregation of keratin filaments, which strengthens the cells and enhances the structural integrity of the epidermis. This process is essential for creating the resilient outer layer of skin that helps protect underlying tissues from damage and dehydration.

In contrast, the other layers mentioned do not contain keratohyalin granules. The Stratum Corneum is primarily composed of dead, flattened keratinized cells that form the outermost protective layer. The Stratum Lucidum, found mainly in thick skin areas, serves as an additional protective layer without the presence of keratohyalin granules. Lastly, the