Which organ is responsible for detoxifying chemicals and metabolizing drugs?

The liver is the primary organ responsible for detoxifying chemicals and metabolizing drugs. It plays a crucial role in processing substances that enter the body, breaking them down into less harmful compounds and making them easier for the body to eliminate. The liver achieves this through a series of enzymatic reactions, including oxidation, reduction, and conjugation.

Notably, the liver contains specialized enzymes that facilitate the metabolism of various substances, including prescription medications, alcohol, and toxins. This metabolic process not only helps in detoxification but also converts these substances into forms that can be excreted by the kidneys or eliminated in bile.

In contrast, while the kidneys play a role in filtering blood and removing waste products from the body, they are not primarily responsible for drug metabolism. The lungs are involved in gas exchange and have some role in metabolizing certain substances, but their primary function is not detoxification. The pancreas is chiefly responsible for producing digestive enzymes and hormones related to blood sugar regulation, rather than detoxifying chemicals. Thus, the liver stands out as the organ specifically tasked with detoxification and drug metabolism.